This study was undertaken to explore gum from Bombax buonopozense calyxes\r\nas a binding agent in formulation of immediate release dosage forms using wet granulation\r\nmethod. The granules were characterized to assess the flow and compression properties\r\nand when compressed, non-compendial and compendial tests were undertaken to assess the\r\ntablet properties for tablets prepared with bombax gum in comparison with those prepared\r\nwith tragacanth and acacia gums. Granules prepared with bombax exhibited good flow and\r\ncompressible properties with angle of repose 28.60�°, Carrâ��s compressibility of 21.30% and\r\nHausnerâ��s quotient of 1.27. The tablets were hard, but did not disintegrate after one hour.\r\nFurthermore, only 52.5% of paracetamol was released after one hour. The drug release\r\nprofile followed zero order kinetics. Tablets prepared with bombax gum have the potential\r\nto deliver drugs in a controlled manner over a prolonged period at a constant rate.
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